Gene information
Official symbol ACVR1
Official full name activin A receptor type 1
Gene type protein-coding gene
Chromosome2q24.1
Alias symbolSKR1; ALK2; ACVR1A
Previous symbolACVRLK2
Gene familyType 1 receptor serine/threonine kinases
Resources
Entrez Gene 90
HGNC HGNC:171
Ensembl ENSG00000115170
Vega OTTHUMG00000131967
UCSC uc010fog.3
GO terms: 30 records
GO Description Category LogP Number of genes Detail
GO:0001568 blood vessel development GO Biological Processes -43.2646440 106 More
GO:0001655 urogenital system development GO Biological Processes -19.5104956 58 More
GO:0001944 vasculature development GO Biological Processes -42.3240404 107 More
GO:0002526 acute inflammatory response GO Biological Processes -34.5980034 29 More
GO:0006954 inflammatory response GO Biological Processes -86.5569367 100 More
GO:0009725 response to hormone GO Biological Processes -49.1091700 138 More
GO:0019838 growth factor binding GO Molecular Functions -18.6841278 23 More
GO:0019900 kinase binding GO Molecular Functions -6.03057706 62 More
GO:0019901 protein kinase binding GO Molecular Functions -6.66055444 59 More
GO:0019955 cytokine binding GO Molecular Functions -19.1485102 24 More
GO:0030335 positive regulation of cell migration GO Biological Processes -66.7331035 139 More
GO:0030855 epithelial cell differentiation GO Biological Processes -14.2408795 69 More
GO:0031960 response to corticosteroid GO Biological Processes -20.1789519 26 More
GO:0033218 amide binding GO Molecular Functions -9.50305686 47 More
GO:0040017 positive regulation of locomotion GO Biological Processes -69.9490345 147 More
GO:0042692 muscle cell differentiation GO Biological Processes -15.1559811 45 More
GO:0042803 protein homodimerization activity GO Molecular Functions -14.2815375 77 More
GO:0048545 response to steroid hormone GO Biological Processes -20.1914989 32 More
GO:0048568 embryonic organ development GO Biological Processes -17.1204114 64 More
GO:0048729 tissue morphogenesis GO Biological Processes -31.7796969 96 More
GO:0048863 stem cell differentiation GO Biological Processes -16.2106470 36 More
GO:0051146 striated muscle cell differentiation GO Biological Processes -10.9431474 33 More
GO:0051272 positive regulation of cellular component movement GO Biological Processes -66.5150412 143 More
GO:0051384 response to glucocorticoid GO Biological Processes -16.9609899 22 More
GO:0060485 mesenchyme development GO Biological Processes -18.0238 46 More
GO:0060537 muscle tissue development GO Biological Processes -18.3336784 54 More
GO:0061061 muscle structure development GO Biological Processes -23.2569142 77 More
GO:0071396 cellular response to lipid GO Biological Processes -37.0669488 98 More
GO:0072132 mesenchyme morphogenesis GO Biological Processes -6.89052200 13 More
GO:2000147 positive regulation of cell motility GO Biological Processes -67.8620360 143 More
Drug-Gene interaction
view
Related drugs: 19 records
Drug name Interaction type Source PMID View
alsterpaullone DTC view
cediranib DTC view
cenisertib DTC view
chembl1997335 DTC view
chembl225519 DTC view
chembl379975 DTC view
chembl406845 DTC view
dactolisib DTC view
dasatinib DTC view
dovitinib DTC view
ilorasertib DTC view
jnj-7706621 DTC view
osi-632 DTC view
pd-0166285 DTC view
rg-1530 DTC view
tae-684 DTC view
tandutinib DTC view
tozasertib DTC view
vandetanib DTC view
Related studies: 2 records
Molecular factor Omics type Application Objective MI type Reference
ACVR1 transcriptomics acute ST elevation myocardial infarction[diagnosis] acute ST elevation myocardial infarction Cederstrom S. Nat Ecol Evol. 2019
activin receptor type-1 proteomics left ventricular remodeling[prognosis (bad)] acute ST elevation myocardial infarction Lin JF et al. Acta Cardiol Sin. 2016
All rights reserved: Soochow University Center for Systems Biology